Search results for "Pulmonary Surfactant-Associated Protein A"

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Humoral autoreactivity directed against surfactant protein-A (SP-A) in rheumatoid arthritis synovial fluids.

2000

SUMMARY SP-A is found principally in the lung, and has been associated with lamellar bodies also found in the synovial joint. Both SP-A and C1q contain collagen-like regions, and SP-A and C1q have some structural similarities, both having a globular head region and a collagen-like tail. Here we are able to show that (i) autoreactivity to SP-A, as expressed by IgG and IgM autoantibodies, is present in synovial fluid (SF) isolated from patients with rheumatoid arthritis (RA); (ii) in absorption experiments only a limited degree of cross-reactivity between autoantibodies reactive with C1q and SP-A is observed; (iii) there is no cross-reactivity between autoantibodies reactive with type II coll…

Pulmonary Surfactant-Associated ProteinsKnee JointProteolipidsImmunologyType II collagenchemical and pharmacologic phenomenamedicine.disease_causeAutoantigensImmunoglobulin GAutoimmunityArthritis RheumatoidRheumatic DiseaseAntigenSynovial jointSynovial FluidmedicineImmunology and AllergySynovial fluidAnimalsHumansskin and connective tissue diseasesAutoantibodiesbiologyPulmonary Surfactant-Associated Protein AChemistryComplement C1qAutoantibodyPulmonary Surfactantsmedicine.anatomical_structureImmunoglobulin MImmunoglobulin MImmunoglobulin GImmunologybiology.proteinBinding Sites AntibodyCollagenPeptidesChickensDimerizationClinical and experimental immunology
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Serum Surfactant Protein D as a Marker of Asthma Severity

2016

Pulmonary and Respiratory MedicinePulmonary Surfactant-Associated Protein Abusiness.industryAsthma severitySurfactant protein DBiomarkerSettore MED/10 - Malattie Dell'Apparato Respiratoriomedicine.diseasePulmonary Surfactant-Associated Protein DCritical Care and Intensive Care MedicineAsthma03 medical and health sciences0302 clinical medicine030228 respiratory systemImmunologyMedicineHumans030212 general & internal medicinePulmonary Surfactant-Associated Protein DbusinessCardiology and Cardiovascular MedicineBiomarkersAsthmaPulmonary Surfactant-Associated Protein AHuman
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